Lauri & Richard Gladstein founded BLOOM'S SYNDROME FOUNDATION in 2004 shortly after learning that their son Milo was diagnosed with the disorder.
Bloom's Syndrome is a very rare inherited genetic disorder, caused by a gene that does not function properly. This creates an unusually high number of breaks or instability along their chromosomes (the structures in the cells of our body that contain our hereditary material - called DNA). This instability causes short stature, immune system deficiencies leading to frequent respiratory and bronchial infections, patchy facial skin colorations, sensitivity to sunlight, sterility, and worst of all, an extraordinarily high risk to develop many cancers and leukemia, at early ages.
Bloom's Syndrome is most common in Jews of Eastern European decent - (Ashkenazi Jews) - and therefore is often classified as a Jewish Genetic Disease.
The Foundation's goal is to fund research aiming at the development of a therapy for Bloom's Syndrome and the prevention of its complications, primarily the significant risk of developing cancers at early ages.
Our foundation seeks financial assistance from institutions and individuals. Approximately 95% of all funds raised by the BSF go directly to the scientific grants that we fund. Our overhead is minimal. Please see BSF Scientific Research on this website to read about the grants we are funding.
Dr. James German and Dr. Maureen Sanz recently created a website to share information about their Bloom's Syndrome Registry. The Registry continues to conduct scientific research and organize data from their many years studying the disorder and meeting with individuals with Bloom's Syndrome. Please see http://med.cornell.edu/bsr.
In addition to Lauri and Richard Gladstein, the foundation's founding Board Members include:
James L. German III, M.D.
Professor, Department of Pediatrics
Weill Medical College of Cornell University
1300 York Avenue New York, NY 10021
Eberhard Passarge, M.D.
Emeritus Director, Department of Human Genetics,
University of Essen School of Medicine
D-45122 Essen, Germanyy
David L. Rimoin, M.D., PhD.
Director, Medical Genetics Institute
Stephen Spielberg Chair
Cedars-Sinai Medical Center
Professor of Pediatrics, Medicine and Human Genetics
David Geffen School of Medicine at UCLA
8700 Beverly Blvd. Suite 665W
Los Angeles, CA 90048